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Sodium Nitroprusside

Catalog No. T0003 CAS 14402-89-2

Synonyms: Sodium Nitroferricyanide, Nitroprusside Sodium, Ro 21-2498

Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.

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Sodium Nitroprusside, CAS 14402-89-2

Pack Size	Availability	Price/USD
50 mg	In stock	$ 40.00
100 mg	In stock	$ 50.00
200 mg	In stock	$ 67.00
500 mg	In stock	$ 87.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.
In vitro	Administering 5 mg/kg of sodium nitroprusside, acting as a nitric oxide donor, effectively mitigates intestinal ischemia-reperfusion injury in rats.
In vivo	Sodium nitroprusside inhibits the proliferation of vascular smooth muscle. As an effective vasodilator, it exhibits pronounced dilation effects particularly in the arterioles and venules. During circulation, sodium nitroprusside decomposes to release nitric oxide (NO), which activates guanylate cyclase in vascular smooth muscle and augments intracellular cyclic guanosine monophosphate (cGMP) production, promoting the relaxation of the smooth muscle and consequent vasodilation.

Synonyms	Sodium Nitroferricyanide, Nitroprusside Sodium, Ro 21-2498
Molecular Weight	261.92
Formula	Na2Fe(CN)5NO
CAS No.	14402-89-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (190.9 mM)

References and Literature

1. Wink DA, et al. Arch Biochem Biophys, 1996, 331(2), 241-8.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Hypertension Compound Library FDA-Approved & Pharmacopeia Drug Library Anti-Cardiovascular Disease Compound Library Approved Drug Library FDA-Approved Drug Library Cardiotoxicity Compound Library Bioactive Compounds Library Max Bioactive Compound Library NO PAINS Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sodium Nitroprusside 14402-89-2 Others Sodium Nitroferricyanide Inhibitor Nitroprusside Sodium inhibit Ro 21-2498 inhibitor

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