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Ro 61-8048

Catalog No. T1896   CAS 199666-03-0

Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.

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Ro 61-8048 Chemical Structure
Ro 61-8048, CAS 199666-03-0
Pack Size Availability Price/USD Quantity
2 mg In stock $ 33.00
5 mg In stock $ 52.00
10 mg In stock $ 70.00
25 mg In stock $ 123.00
50 mg In stock $ 198.00
100 mg In stock $ 315.00
200 mg In stock $ 568.00
500 mg In stock $ 913.00
1 mL * 10 mM (in DMSO) In stock $ 58.00
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Purity: 99.91%
Purity: 98.86%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.
Targets&IC50 KMO:37 nM
Molecular Weight 421.45
Formula C17H15N3O6S2
CAS No. 199666-03-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 4.2 mg/mL (10 mM)

DMSO: 42.2 mg/mL (100 mM)

TargetMolReferences and Literature

1. Röver S, et al. J Med Chem. 1997, 40(26), 4378-4385. 2. Cozzi A, et al. J Cereb Blood Flow Metab. 1999, 19(7), 771-777. 3. Richter A, et al. Eur J Pharmacol. 2003, 478(1), 47-52. 4. Khalil OS, et al. Eur J Neurosci. 2014, 39(10), 1558-1571.

Related compound libraries

This product is contained In the following compound libraries:
Metabolism Compound Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Cardiovascular Disease Compound Library Inhibitor Library Orally Active Compound Library Preclinical Compound Library Anti-Metabolism Disease Compound Library

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Fenclonine (R)-Nepicastat HCl Telotristat ethyl Rodatristat ethyl pCPA methyl ester hydrochloride p-Ethynylphenylalanine Mildronate LX-1031

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ro 61-8048 199666-03-0 Metabolism Hydroxylase NMDA Ro 61 8048 inhibit dystonia Inhibitor hydroxylase Ro 618048 kynurenine inhibitor

 

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