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R1487 Hydrochloride

R1487 Hydrochloride
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R1487 Hydrochloride

Catalog No. T7162Cas No. 449808-64-4
R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$665 days
5 mg$1075 days
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Product Introduction

Bioactivity
Description
R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.
AliasR1487 (Hydrochloride)
Chemical Properties
Molecular Weight424.83
FormulaC19H19ClF2N4O3
Cas No.449808-64-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 20.83 mg/mL (49.03 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3539 mL11.7694 mL23.5388 mL117.6941 mL
5 mM0.4708 mL2.3539 mL4.7078 mL23.5388 mL
10 mM0.2354 mL1.1769 mL2.3539 mL11.7694 mL
20 mM0.1177 mL0.5885 mL1.1769 mL5.8847 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg,each TargetMol | Animal experiments animal weighs 20 g, and the dosage volume is 100 μL. A total of TargetMol | Animal experiments 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
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Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

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