keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 75.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 192.00 | |
100 mg | In stock | $ 287.00 | |
200 mg | In stock | $ 431.00 | |
500 mg | In stock | $ 713.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 81.00 |
Description | Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity. |
Synonyms | HM 781-36B hydrochloride, NOV120101 hydrochloride |
Molecular Weight | 527.8 |
Formula | C23H22Cl3FN4O3 |
CAS No. | 1429757-68-5 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (42.63 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Poziotinib hydrochloride 1429757-68-5 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR Poziotinib Hydrochloride NOV 120101 Hydrochloride NOV-120101 Hydrochloride HM 781-36B Hydrochloride HM 781-36B hydrochloride NOV120101 Hydrochloride NOV120101 hydrochloride inhibitor inhibit