Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 67.00 | |
25 mg | In stock | $ 117.00 | |
50 mg | In stock | $ 187.00 | |
100 mg | In stock | $ 337.00 | |
200 mg | In stock | $ 492.00 | |
500 mg | In stock | $ 786.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 52.00 |
Description | Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM. |
Targets&IC50 | MKLP2:1.35 μM, MKLP2:3.36 Μm(Ki) |
In vitro | Paprotrain-treated porcine oocytes suffer failure of nuclear maturation.?The number of oocytes arrested at early MI stage increase in a dose-dependent manner after KIF20A activity inhibition, while the percentage of oocytes that reach ATI and MII stages decrease after treatment[3]. |
Synonyms | (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile |
Molecular Weight | 245.28 |
Formula | C16H11N3 |
CAS No. | 57046-73-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (407.70 mM)
You can also refer to dose conversion for different animals. More
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Paprotrain 57046-73-8 Cytoskeletal Signaling Kinesin Inhibitor (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile inhibit inhibitor