Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein.
Description | Nucleocidin is an antitrypanosomal antibiotic. Nucleocidin inhibiting the transfer of labeled amino acid from S-RNA to protein. |
In vitro | Nucleocidin shows inhibition occurs at low concentrations, however, it is not possible to obtain complete inhibition at 10-3 M. Essentially complete inhibition is obtained at 10-3 M puromycin, and only at the lowest concentrations is any lag detectable. It seems that Nucleocidin exhibits the pattern typical of many antibiotics, i.e. it inhibits incorporation at a stage subsequent to the formation of aminoacyl-S-RNA. An appreciable lag occurs before any inhibition by Nucleocidin is detectable, and the length of this lag period varies inversely with the concentration of Nucleocidin. Similar results are obtained when Nucleocidin is added to the cell-free system from reticulocytes . |
Synonyms | NSC 521007, 4'-Fluoro-5'-O-sulfamoyladenosine |
Molecular Weight | 364.31 |
Formula | C10H13FN6O6S |
CAS No. | 24751-69-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Nucleocidin 24751-69-7 代谢 NADPH NSC 521007 4'-Fluoro-5'-O-sulfamoyladenosine Inhibitor inhibitor inhibit