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Mogroside IIe

Catalog No. TN1056 CAS 88901-38-6

Mogroside IIe is a major bioactive component of unripe S. grosvenorii fruit that downregulates the IL-9/IL-9 receptor pathway.

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Mogroside IIe, CAS 88901-38-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 89.00
5 mg	In stock	$ 219.00
10 mg	In stock	$ 323.00
25 mg	In stock	$ 523.00
50 mg	In stock	$ 757.00
100 mg	In stock	$ 1,060.00
1 mL * 10 mM (in DMSO)	In stock	$ 340.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Mogroside IIe is a major bioactive component of unripe S. grosvenorii fruit that downregulates the IL-9/IL-9 receptor pathway.
In vitro	Mogroside IIE decreased the activity of trypsin and cathepsin B induced by cerulein plus lipopolysaccharide (LPS) in the pancreatic acinar cell line AR42J and primary acinar cells in a dose- and time-dependent manner[1].
In vivo	Mogroside IIE treatment decreased the levels of serum lipase and serum amylase in mice injected with cerulein plus LPS without influencing inflammation significantly. A multi-cytokine array revealed that mogroside IIE decreased the level of interleukin 9 (IL-9) in AP mice[1].
Source	Natural Products > Cucurbitaceae > Siraitia

Molecular Weight	801.01
Formula	C42H72O14
CAS No.	88901-38-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (124.84 mM)

References and Literature

1. Xiao J, et al. Mogroside IIE Inhibits Digestive Enzymes via Suppression of Interleukin 9/Interleukin 9 Receptor Signalling in Acute Pancreatitis. Front Pharmacol. 2020 Jun 10;11:859. 2. Wang L, et al. Cucurbitane glycosides derived from mogroside IIE: structure-taste relationships, antioxidant activity, and acute toxicity. Molecules. 2014 Aug 20;19(8):12676-89.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Pyroptosis Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Anti-Tumor Natural Product Library Bioactive Compound Library Traditional Chinese Medicine Monomer Library Food as Medicine Compound Library Natural Product Library for HTS Selected Plant-Sourced Compound Library Natural Product Library

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Keywords

Mogroside IIe 88901-38-6 Immunology/Inflammation IL Receptor inhibit Inhibitor inhibitor

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