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Managlinat dialanetil

Catalog No. T16009 CAS 347870-26-2

Synonyms: CS-917, MB06322

Managlinat dialanetil is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase). It is used for the treatment of type 2 diabetes.

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Managlinat dialanetil, CAS 347870-26-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Managlinat dialanetil is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase). It is used for the treatment of type 2 diabetes.
In vivo	After oral administration, in Zucker diabetic fatty (ZDF) rats, Managlinat dialanetil dose-dependently inhibits GNG as well as lower basal and postprandial blood glucose levels[1].

Synonyms	CS-917, MB06322
Molecular Weight	N/A
CAS No.	347870-26-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Wang Y, et al. Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes. Curr Opin Investig Drugs. 2007 Oct;8(10):849-58.

Related Products

Related compounds with same targets

Pralatrexate Trioxsalen Fanotaprim Brodimoprim WR99210 Managlinat dialanetil Lometrexol Pelitrexol

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Managlinat dialanetil 280782-97-0 DNA损伤和修复代谢细胞周期 DHFR MB06322 CS-917 Inhibitor inhibitor inhibit

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