Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 57.00 | |
5 mg | In stock | $ 139.00 | |
10 mg | In stock | $ 222.00 | |
25 mg | In stock | $ 447.00 | |
50 mg | In stock | $ 659.00 | |
100 mg | In stock | $ 939.00 |
Description | L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a. |
Targets&IC50 | oxytocin receptor:(ki)19 nM, vasopressin V1a receptor:3.7 nM(ki) |
In vivo | L-371,257 (0.5 and 1.0 mg/kg; i.p.) stimulates weight gain (10.5 g) relative to vehicle treatment (4.7 g) in rats[3]. |
Molecular Weight | 507.58 |
Formula | C28H33N3O6 |
CAS No. | 162042-44-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8.1mg/mL (16mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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L-371,257 162042-44-6 Endocrinology/Hormones GPCR/G Protein Oxytocin Receptor Vasopressin Receptor L371,257 L 371,257 inhibitor inhibit