Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 30.00 | |
25 mg | In stock | $ 64.00 | |
50 mg | In stock | $ 97.00 | |
100 mg | In stock | $ 163.00 | |
200 mg | In stock | $ 243.00 | |
500 mg | In stock | $ 397.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 52.00 |
Description | ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors. |
Cell Research | A549 cells ( 75% confluent) in 10-cm dishes are treated with DMSO (0.1%), TSA (500 nM), or tubacin (2 μM) for 4.5 h, and then either DMSO (0.1%) or ITSA1 (50 μM) is added for an additional 17.5 h. Samples are rinsed in PBS, trypsinized, and fixed for 2 h in 70% ethanol 30% PBS (4°C). Cells then are washed once in PBS and stored overnight in PBS (4°C).(Only for Reference) |
Synonyms | ITSA1 |
Molecular Weight | 292.12 |
Formula | C13H7Cl2N3O |
CAS No. | 200626-61-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 54 mg/mL (184.9 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 5 mg/mL (17.12 mM)
You can also refer to dose conversion for different animals. More
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ITSA-1 200626-61-5 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC inhibit Histone deacetylases Inhibitor ITSA1 ITSA 1 inhibitor