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Hinesol

Catalog No. T19960 CAS 23811-08-7

Synonyms: (-)-Hinesol

Hinesol is a unique sesquiterpenoid isolated from Atractylodes lancea rhizome. Hinesol has been found to induce apoptosis through the JNK signaling pathway in HL-60 cells.

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Hinesol, CAS 23811-08-7

Pack Size	Availability	Price/USD	Quantity
20 mg	Inquiry	$ 2,250.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Hinesol is a unique sesquiterpenoid isolated from Atractylodes lancea rhizome. Hinesol has been found to induce apoptosis through the JNK signaling pathway in HL-60 cells.

Synonyms	(-)-Hinesol
Molecular Weight	222.37
Formula	C15H26O
CAS No.	23811-08-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. He JH, Niu YF, Li JX, Wang LB, Zi TP, Yu S, Tao J. [Studies on terpenoids from Zygophyllum fabago]. Zhongguo Zhong Yao Za Zhi. 2015 Dec;40(23):4634-8. Chinese. PubMed PMID: 27141675. 2. Kasaian J, Asili J, Iranshahi M. Sulphur-containing compounds in the essential oil of Ferula alliacea roots and their mass spectral fragmentation patterns. Pharm Biol. 2016 Oct;54(10):2264-8. doi: 10.3109/13880209.2016.1152279. Epub 2016 Mar 10. PubMed PMID: 26963574. 3. Zhang Y, Miki S, Chen ML, Takeda X, Zhao DY, Kang LP, Guo LP. [Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea]. Zhong Yao Cai. 2015 Mar;38(3):429-32. Chinese. PubMed PMID: 26495637. 4. Masuda Y, Kadokura T, Ishii M, Takada K, Kitajima J. Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells. J Nat Med. 2015 Jul;69(3):332-9. doi: 10.1007/s11418-015-0897-5. Epub 2015 Apr 2. PubMed PMID: 25833731.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Hinesol 23811-08-7 (-)-Hinesol inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.