Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gemcitabine-O-Si(di-iso)-O-Mc, a drug-linker conjugate for Antibody-Drug Conjugates (ADC), exhibits potent antitumor activity. It incorporates Gemcitabine, a pyrimidine nucleoside analog antimetabolite and antineoplastic agent, connected through the ADC linker[1].
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Description | Gemcitabine-O-Si(di-iso)-O-Mc, a drug-linker conjugate for Antibody-Drug Conjugates (ADC), exhibits potent antitumor activity. It incorporates Gemcitabine, a pyrimidine nucleoside analog antimetabolite and antineoplastic agent, connected through the ADC linker[1]. |
In vitro | Antibody-drug conjugates (ADC) seamlessly integrate therapeutic monoclonal antibodies (mAb) with potent toxins via a linker, which remains stable in systemic circulation and cleaves selectively within targeted cells[1]. |
Molecular Weight | 558.65 |
Formula | C24H36F2N4O7Si |
CAS No. | T17985 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Gemcitabine-O-Si(di-iso)-O-Mc T17985 Others GemcitabineOSi(diiso)OMc Gemcitabine O Si(di iso) O Mc inhibitor inhibit