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Ergosterol peroxide

Catalog No. TMA1743 CAS 2061-64-5

Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pro-apoptotic protein Puma and Bax to induce cancer cell death.Ergosterol peroxide can ameliorate TGF-β1-induced activation of kidney fibroblasts, it has the potential to be developed as a therapeutic agent to prevent renal fibrosis.

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Ergosterol peroxide, CAS 2061-64-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	428.657
Formula	C28H44O3
CAS No.	2061-64-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ergosterol peroxide 2061-64-5 JAK/STAT信号通路 MAPK信号通路 PI3K/Akt/mTOR信号通路表观遗传蛋白酪氨酸激酶干细胞微生物学细胞骨架细胞周期血管生成 CDK ERK Antifection Akt JAK JNK VEGFR Wnt/beta-catenin p38 MAPK STAT Inhibitor inhibitor inhibit

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