Ergosterol peroxide

Name: Ergosterol peroxide
Brand: TargetMol
SKU: TMA1743
Rating: 4.5 (1 reviews)

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Catalog No. TMA1743Cas No. 2061-64-5

Alias NSC31324, NSC 31324

Ergosterol peroxide (NSC 31324) is a derivative from mushrooms with anti-tumor, pro-apoptotic anti-mycobacterial and anti-proliferative activities.Ergosterol peroxide has anti-inflammatory and antioxidant activities and is toxic to parasites.

Ergosterol peroxide

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Catalog No. TMA1743Alias NSC31324, NSC 31324Cas No. 2061-64-5

Pack Size	Price	Availability
500 μg	TBD	35 days
1 mg	TBD	35 days
5 mg	TBD	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Ergosterol peroxide (NSC 31324) is a derivative from mushrooms with anti-tumor, pro-apoptotic anti-mycobacterial and anti-proliferative activities.Ergosterol peroxide has anti-inflammatory and antioxidant activities and is toxic to parasites.
Targets&IC50	T. cruzi:6.74 µg/mL
In vitro	Ergosterol peroxide showed an IC50 of 6.74 µg/mL against T. cruzi, but did not lyse erythrocytes even at concentrations as high as 1600 µg/mL and had no toxic effects on mammalian cells. In vitro experiments showed that Ergosterol peroxide exhibited significant lysogenic activity when interacting with Trypanosoma cruzi, possibly due to rupture of the parasite cell membrane. [1]
Alias	NSC31324, NSC 31324

Chemical Properties

Molecular Weight	428.65
Formula	C₂₈H₄₄O₃
Cas No.	2061-64-5
Smiles	C[C@@]12[C@@]3([C@@]4([C@]5([C@](C)(CC3)[C@@]([C@@H](/C=C/[C@@H](C(C)C)C)C)(CC5)[H])[H])C=C[C@@]1(OO4)C[C@@H](O)CC2)[H]
Relative Density.	1.08g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc