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Product Introduction

Bioactivity

Description

Diethyl malonate is naturally occurring in grapes and strawberries.

Chemical Properties

Molecular Weight	160.17
Formula	C₇H₁₂O₄
Cas No.	105-53-3
Smiles	CCOC(=O)CC(=O)OCC
Relative Density.	1.055

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 10 mg/mL (62.43 mM), Sonication is recommended.

DMSO: 60 mg/mL (374.6 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.2434 mL	31.2168 mL	62.4337 mL	312.1683 mL
5 mM	1.2487 mL	6.2434 mL	12.4867 mL	62.4337 mL
10 mM	0.6243 mL	3.1217 mL	6.2434 mL	31.2168 mL
20 mM	0.3122 mL	1.5608 mL	3.1217 mL	15.6084 mL
50 mM	0.1249 mL	0.6243 mL	1.2487 mL	6.2434 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0624 mL	0.3122 mL	0.6243 mL	3.1217 mL

Sci Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Diethyl MalonateDiethyl malonate