Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DKM 2-93 is a relatively selective inhibitor of UBA5(IC50 : 430 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 30.00 | |
50 mg | In stock | $ 45.00 | |
100 mg | In stock | $ 68.00 | |
200 mg | In stock | $ 119.00 | |
500 mg | In stock | $ 237.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | DKM 2-93 is a relatively selective inhibitor of UBA5(IC50 : 430 μM). |
Targets&IC50 | UBA5:430 μM |
In vitro | Covalent ligand DKM 2-93 that impairs pancreatic cancer cell survival and in vivo tumor growth through covalently modifying the catalytic cysteine of the ubiquitin-like modifier activating enzyme 5 (UBA5), thereby inhibiting its activity as a protein that activates the ubiquitin-like protein UFM1 to UFMylate proteins. |
Molecular Weight | 243.69 |
Formula | C11H14ClNO3 |
CAS No. | 65836-72-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (615.54 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DKM 2-93 65836-72-8 Ubiquitination E1/E2/E3 Enzyme E1 activating enzyme Ubiquitin activating enzyme Inhibitor Ubiquitin conjugating enzyme Ubiquitin ligase inhibit E3 ligating enzyme E2 conjugating enzyme DKM 293 DKM 2 93 inhibitor