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D2343

Catalog No. T15042 CAS 72734-63-5

D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.

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D2343, CAS 72734-63-5

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.
In vitro	D2343 shows in addition an alpha 1-receptor inhibitory activity [1]. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM [2].
In vivo	D2343 demonstrates a capacity to relax uterine muscles comparably or more effectively than Terbutaline, particularly when assessed in rabbit and rat preparations. This comparison extends to oestrogenized uterine preparations from rats and myometrial strips from both species, showcasing D2343's potential efficacy against the beta 2-agonist Terbutaline [1].

Molecular Weight	329.43
Formula	C20H27NO3
CAS No.	72734-63-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Olsson OA, et al. The effects in myometrial preparations of D2343, a beta 2-adrenoceptor agonist possessing alpha 1-receptor blocking qualities. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):391-7. 2. Olsson OA, et al. The effect of D2343 in transmurally stimulated rabbit isthmus muscle. Acta Pharmacol Toxicol (Copenh). 1985 May;56(5):427-30.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

D2343 72734-63-5 GPCR/G Protein Neuroscience Adrenergic Receptor D-2343 D 2343 inhibitor inhibit

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