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Cheilanthifoline

Catalog No. TN1484 CAS 483-44-3

Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts.

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Cheilanthifoline, CAS 483-44-3

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Purity: 98%

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Description

In vitro

A phytochemical investigation for the rhizome extract from Sinomenium acutum (Menispermaceae) resulted in the isolation of several active principles responsible for the anti-osteoclastogenic property of the extract, together with related isoquinoline alkaloids (1-13) including two new compounds, 1 and 2. Among isolated compounds, salutaridine (7), dauricumine (10), Cheilanthifoline (12), and dauriporphine (13) were observed to give significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts, respectively[1]

Molecular Weight	325.36
Formula	C19H19NO4
CAS No.	483-44-3

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Powder: -20°C for 3 years

In solvent: -80°C for 2 years

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( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Anti-osteoclastogenic effects of isoquinoline alkaloids from the rhizome extract of Sinomenium acutum.Arch Pharm Res. 2016 May;39(5):713-20.

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Keywords

Cheilanthifoline 483-44-3 Microbiology/Virology NF-Κb Antifection NF-κB Inhibitor inhibitor inhibit

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