Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors). |
Targets&IC50 | 5-HT2B:7.19 (pEC50), 5-HT2C:9.96 (pEC50), 5-HT2A:6.81 (pEC50) |
In vitro | Similar to currently available antipsychotic drugs, CP-809101 dose-dependently inhibited conditioned avoidance responding (CAR, ED50 = 4.8 mg/kg, sc). CP-809101 antagonized both PCP- and d-amphetamine-induced hyperactivity with ED50 values of 2.4 and 2.9 mg/kg (sc), respectively and also reversed an apomorphine induced-deficit in prepulse inhibition. At doses up to 56 mg/kg, CP-809101 did not produce catalepsy. Thus, the present results demonstrate that the 5-HT2C agonist, CP-809101, has a pharmacological profile similar to that of the atypical antipsychotics with low extrapyramidal symptom liability. |
Molecular Weight | 304.77 |
Formula | C15H17ClN4O |
CAS No. | 479683-64-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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CP-809101 479683-64-2 GPCR/G Protein Neuroscience 5-HT Receptor CP809101 CP 809101 inhibitor inhibit