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BI-7273

Catalog No. T6783   CAS 1883429-21-7

BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
BI-7273 Chemical Structure
BI-7273, CAS 1883429-21-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 45.00
2 mg In stock $ 64.00
5 mg In stock $ 97.00
10 mg In stock $ 187.00
25 mg In stock $ 377.00
50 mg In stock $ 597.00
100 mg In stock $ 849.00
1 mL * 10 mM (in DMSO) In stock $ 118.00
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Purity: 99.72%
Purity: 99.57%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.
Targets&IC50 BRD7:117 nM, BRD9:19 nM
In vitro BI-7273 blocks EOL-1 cell proliferation with EC50 of 1400 nM. BI-7273 (1 μM) is active in U2OS cell lines. BI-7273 (10 μM) shows an inhibition below 40% against 31 kinases[1].
Cell Research Cells are grown in 50 μL medium as specified by the supplier for 7 days starting with 500 and with 1000 cells per well of a 384 well plate in the presence of varying concentrations of compound before measuring viability via cellular ATP levels using the cell titer glow assay.
Molecular Weight 353.41
Formula C20H23N3O3
CAS No. 1883429-21-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 65 mg/mL (183.9 mM)

DMSO: 65 mg/mL (183.9 mM)

TargetMolReferences and Literature

1. Martin LJ, et al. J Med Chem. 2016, 59(10):4462-4475. 2. Zhang W, Chen F, Chen R, et al. Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes[J]. Nucleic acids research. 2019.

TargetMolCitations

1. Zhang W, Chen F, Chen R, et al. Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes. Nucleic Acids Research. 2019

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Inhibitor Library NO PAINS Compound Library Histone Modification Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library Chromatin Modification Compound Library PPI Inhibitor Library Reprogramming Compound Library Epigenetics Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BI-7273 1883429-21-7 Chromatin/Epigenetic Epigenetic Reader Domain inhibit BI 7273 Inhibitor BI7273 inhibitor

 

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