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Afatinib D6

Catalog No. T10256 CAS 1313874-96-2

Synonyms: BIBW 2992 D6

Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible <a href="/target/EGFR" style="display: inline; color: #c13a36">EGFR</a> family inhibitor.

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Afatinib D6, CAS 1313874-96-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.

Synonyms	BIBW 2992 D6
Molecular Weight	491.98
Formula	C24H25ClFN5O3
CAS No.	1313874-96-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Li D, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008 Aug 7;27(34):4702-11.

Related Products

Related compounds with same targets

Neolinine Hirsutenone 1,5-Dihydroxyxanthone Marinobufogenin Matuzumab EGFR-IN-16 Cisapride hydrate AG-825

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Afatinib D6 1313874-96-2 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR Afatinib D-6 BIBW 2992 D6 Inhibitor inhibitor inhibit

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