Powder: -20°C for 3 years
In solvent: -80°C for 2 years
AdipoRon is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).
Description | AdipoRon is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM). |
Targets&IC50 | AdipoR2:3.1 μM(Kd), AdipoR1:1.8 μM(Kd) |
Cell Research | The effects of AdipoRon on the proliferation of parenchymal and non-parenchymal hepatocytes are evaluated in vitro via L02 and RAW264.7, by MTT assay as described with slight modification: 100 μL cells suspension (6×104/mL) are seeded in a 96-well plate and incubated for 18 h. Fresh media with AdipoRon are added at specified concentrations, and the incubations continue for a further 24 h. Then cells are incubated for 4 h with 0.5 mg/mL of MTT, and analyzed in a microplate reader at 490 nm. Each group is performed in six replications. The mean absorbance values corrected for a blank (medium only) are calculated as percentages of survival. |
Synonyms | SC-396658 |
Molecular Weight | 428.52 |
Formula | C27H28N2O3 |
CAS No. | 924416-43-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: <1 mg/mL
Ethanol: 47 mg/mL (109.7 mM)
DMSO: 80 mg/mL (186.7 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AdipoRon 924416-43-3 GPCR/G Protein Adiponectin receptor Adiponectin Receptor AdipoRs Inhibitor inhibit SC-396658 inhibitor