Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AR-M 1896 Acetate is the selective agonist of GalR2.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 941.00 | |
5 mg | In stock | $ 1,880.00 | |
10 mg | In stock | $ 2,560.00 | |
25 mg | In stock | $ 3,780.00 | |
50 mg | In stock | $ 5,130.00 | |
100 mg | In stock | $ 6,920.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 3,910.00 |
Description | AR-M 1896 Acetate is the selective agonist of GalR2. |
Targets&IC50 | GalR2:1.76 nM, GalR1 (human):879 Nm |
In vitro | Removal of the glycine residue in position 1 resulted in AR-M1896 with almost unchanged GalR2 affinity and functional activity, and 500-fold selectivity for GalR2-Rs over GalR1-Rs[1].? |
In vivo | In normal rats mechanical and cold allodynia of the hindpaw are induced by intrathecal infusion of low-dose galanin. The same effect is seen with equimolar doses of AR-M1896 or AR-M961 (an agonist both at GalR1 and GalR2 receptors). In allodynic Bennett model rats, the mechanical threshold dose-dependently increased after intrathecal injection of a high AR-M961dose, whereas no effect was observed in the control or AR-M1896 group. No effect of either compounds was observed in nonallodynic Bennett model rats[1]. |
Synonyms | AR-M 1896 Acetate (367518-31-8 Free base) |
Molecular Weight | 1196.35 |
Formula | C56H85N13O16 |
CAS No. | T21646L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (45.97 mM)
You can also refer to dose conversion for different animals. More
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AR-M 1896 Acetate T21646L GPCR/G Protein Neuroscience Neuropeptide Y Receptor 367518-31-8 Free base ARM 1896 Acetate AR M 1896 Acetate AR-M-1896 Acetate 367518-31-8 AR-M 1896 Acetate (367518-31-8 Free base) AR-M1896 Acetate inhibitor inhibit