store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM. The binding of AMP-PCP disodium contributes to the formation of an active homodimer of Hsp90.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 293.00 | |
25 mg | In stock | $ 497.00 | |
50 mg | In stock | $ 693.00 | |
100 mg | In stock | $ 982.00 | |
500 mg | In stock | $ 1,960.00 |
Description | AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM. The binding of AMP-PCP disodium contributes to the formation of an active homodimer of Hsp90. |
Targets&IC50 | HSP90:3.8 μM (kd) |
In vitro | Under the promotion of AMP-PCP disodium binding, the formation of Hsp135 active homodimers was enhanced by promoting the characteristic slow-effect conformational exchange of cap region ( A90-G117 ) and surrounding region residues ( A141-A111 ). A total of 90 non-proline residues were identified in the triple-labeled Hsp170 and AMP-PCP binding [ 1 ]. |
Molecular Weight | 549.17 |
Formula | C11H16N5Na2O12P3 |
CAS No. | 7414-56-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 80 mg/mL (145.67 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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AMP-PCP disodium 7414-56-4 Cytoskeletal Signaling Metabolism HSP AMPPCP disodium AMP-PCP AMP PCP disodium inhibitor inhibit