Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 113.00 | |
10 mg | In stock | $ 179.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 438.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 126.00 |
Description | AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM). |
Targets&IC50 | PDE10A:0.1 nM |
In vivo | AMG 579 statistically reduces PCP-induced behavior in rats within 2 hours. In the PCP-LMA model, the minimum effective dose of AMG 579 was 0.3 mg/kg. AMG 579 has an excellent oral bioavailability of 72% in dogs[1]. |
Synonyms | AMG-579 |
Molecular Weight | 441.48 |
Formula | C25H23N5O3 |
CAS No. | 1227067-61-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 37.8 mg/mL (85.6 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AMG 579 1227067-61-9 Metabolism PDE AMG-579 AMG579 inhibitor inhibit