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25,26-Dihydroxyvitamin D3

Catalog No. T13490Cas No. 29261-12-9
Alias 25,26-Dihydroxycholecalciferol

25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a vitamin D3 metabolite and a precursor compound for the synthesis of 25-hydroxyvitamin D.

25,26-Dihydroxyvitamin D3

25,26-Dihydroxyvitamin D3

Purity: 95.47%
Catalog No. T13490Alias 25,26-DihydroxycholecalciferolCas No. 29261-12-9
25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a vitamin D3 metabolite and a precursor compound for the synthesis of 25-hydroxyvitamin D.
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Purity:95.47%
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Product Introduction

Bioactivity
Description
25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a vitamin D3 metabolite and a precursor compound for the synthesis of 25-hydroxyvitamin D.
In vitro
24,25 and 25,26 diOHD3 (0.125-0.250 mug) were able to increase calcium absorption in rats maintained on a calcium-deficient diet, but failed to do it in rats on a normal calcium diet. Bilateral nephrectomy suppressed this effect. The 'bone calcium mobilization' of both derivatives was measured in vitamin D and calcium- or phosphorus-deprived rats after one intravenous dose. When serum calcium was initially low, 24,25 and 25,26 diOHD3 increased serum calcium moderately, but the increment was only significant with 24,25 diOHD3 [2].
In vivo
24,25 and 25,26-Dihydroxyvitamin D3 (0.125-0.250 mug) were able to increase calcium absorption in rats maintained on a calcium-deficient diet, but failed to do it in rats on a normal calcium diet. Bilateral nephrectomy suppressed this effect. The "bone calcium mobilization" of both derivatives was measured in vitamin D and calcium- or phosphorus-deprived rats after one intravenous dose. When serum calcium was initially low, 24,25 and 25,26-Dihydroxyvitamin D3 increased serum calcium moderately, but the increment was only significant with 24,25-Dihydroxyvitamin D3 [2].
Alias25,26-Dihydroxycholecalciferol
Chemical Properties
Molecular Weight416.64
FormulaC27H44O3
Cas No.29261-12-9
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (192.01 mM.), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4002 mL12.0008 mL24.0015 mL120.0077 mL
5 mM0.4800 mL2.4002 mL4.8003 mL24.0015 mL
10 mM0.2400 mL1.2001 mL2.4002 mL12.0008 mL
20 mM0.1200 mL0.6000 mL1.2001 mL6.0004 mL
50 mM0.0480 mL0.2400 mL0.4800 mL2.4002 mL
100 mM0.0240 mL0.1200 mL0.2400 mL1.2001 mL

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