Powder: -20°C for 3 years | In solvent: -80°C for 1 year
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide. Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the human cornea to yield the corresponding free acid, with a conversion rate of about 25 μg/cornea/24 hours. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. 15(R)-17-phenyl trinor PGF2α is the 15-epi, or unnatural" isomer of this active free acid metabolite. It has much diminished FP receptor-mediated activity
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 160.00 | |
5 mg | 35 days | $ 686.00 | |
10 mg | 35 days | $ 1,240.00 |
Description | 17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide. Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the human cornea to yield the corresponding free acid, with a conversion rate of about 25 μg/cornea/24 hours. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. 15(R)-17-phenyl trinor PGF2α is the 15-epi, or unnatural" isomer of this active free acid metabolite. It has much diminished FP receptor-mediated activity |
Synonyms | 15(R)-17-phenyl trinor Prostaglandin F2α |
Molecular Weight | 388.5 |
Formula | C23H32O5 |
CAS No. | 41639-71-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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15(R)-17-phenyl trinor Prostaglandin F2α 41639-71-8 1517-phenyl trinor Prostaglandin F2alpha 1517-phenyl trinor Prostaglandin F2α 15(R) 17 phenyl trinor Prostaglandin F2α 1517-phenyl trinor Prostaglandin F2a 15(R)17phenyl trinor Prostaglandin F2α 15(R)-17-phenyl trinor Prostaglandin F-2α inhibitor inhibit