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(±)-AC 7954 hydrochloride

Name: (±)-AC 7954 hydrochloride
Brand: TargetMol
SKU: T22476
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22476Cas No. 477313-09-0

(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.

(±)-AC 7954 hydrochloride

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Purity: 99.97%

Catalog No. T22476Cas No. 477313-09-0

(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	-	In Stock
5 mg	$119	-	In Stock
10 mg	$176	-	In Stock
25 mg	$297	-	In Stock
50 mg	$433	-	In Stock
100 mg	$592	-	In Stock
200 mg	$783	-	In Stock
1 mL x 10 mM (in DMSO)	$128	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

(±)-AC 7954 hydrochloride AI Summary

(±)-AC 7954 hydrochloride exhibits potency against human and rat Urotensin 2 receptors with EC50 values of 316.23 nM and 199.53 nM, respectively. Displaying moderate lipophilicity with a LogD value of 2.1 and a dissociation constant with a pKa of 8.7, (±)-AC 7954 hydrochloride shows potential pharmacological effects related to Urotensin 2 receptor modulation..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.

Chemical Properties

Molecular Weight	366.28
Formula	C₁₉H₂₁Cl₂NO₂
Cas No.	477313-09-0
Smiles	Cl.O=C1OC(C2=CC=C(Cl)C=C2)(CC=3C=CC=CC13)CCN(C)C
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 67.5 mg/mL (184.29 mM), Sonication is recommended.

DMSO: 45 mg/mL (122.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.7302 mL	13.6508 mL	27.3015 mL	136.5076 mL
5 mM	0.5460 mL	2.7302 mL	5.4603 mL	27.3015 mL
10 mM	0.2730 mL	1.3651 mL	2.7302 mL	13.6508 mL
20 mM	0.1365 mL	0.6825 mL	1.3651 mL	6.8254 mL
50 mM	0.0546 mL	0.2730 mL	0.5460 mL	2.7302 mL
100 mM	0.0273 mL	0.1365 mL	0.2730 mL	1.3651 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc