(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist

(R)-Praziquantel modulates serotoninergic signaling within a concentration range that effectively regulates the vascular tone of mesenteric blood vessels, where adult parasites inhabit their host. This critical anthelmintic demonstrates a wide, cross-species polypharmacology, with (R)-Praziquantel influencing signaling events in both the host and the parasite.