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(-)-Oxypeucedanin hydrate

Catalog No. T5808 CAS 133164-11-1

Synonyms: OXYPEUCEDANIN HYDRATE

(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.

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(-)-Oxypeucedanin hydrate Chemical Structure

(-)-Oxypeucedanin hydrate, CAS 133164-11-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 129.00
5 mg	In stock	$ 320.00
10 mg	In stock	$ 475.00
25 mg	In stock	$ 779.00
50 mg	In stock	$ 1,090.00
1 mL * 10 mM (in DMSO)	In stock	$ 330.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
In vitro	Oxypeucedanin exhibited marginal toxicity on normal fibroblast cells and sensitive parental mouse lymphoma cells;?furthermore, they were less toxic on multidrug resistant lymphoma cells.? Oxypeucedanin showed moderate MDR reversing activity.?In the checkerboard assay, oxypeucedanin and heraclenin showed slight synergistic effect with doxorubicin.?These compounds might improve the cytotoxic effect of the standard chemotherapeutic drug doxorubicin.
Cell Research	Pure compounds were isolated from the extract of aerial parts of the plant by chromatographic methods.Bioactivities were tested on multidrug resistant and sensitive mouse T-lymphoma cell lines.The inhibition of the cancer MDR efflux pump ABCB1 was evaluated by flow cytometry (at 2 and 20 μM).A checkerboard microplate method was applied to study the interactions of furocoumarins and doxorubicin.Toxicity was studied using normal murine NIH/3T3 fibroblasts.

Synonyms	OXYPEUCEDANIN HYDRATE
Molecular Weight	304.29
Formula	C16H16O6
CAS No.	133164-11-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (180.75 mM)

References and Literature

1. Mottaghipisheh J , Márta Nové, Spengler G , et al. Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia[J]. Pharmaceutical Biology, 2018, 56(1):658-664.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library NO PAINS Compound Library Traditional Mongolian Medicine Compound Library Tibetan medicine Compound Library Chinese Pharmacopoeia Natural Product Library Natural Product Library Selected Plant-Sourced Compound Library RO5 Drug-like Natural Product Library Natural Product Library for HTS PBCRBS Traditional Chinese Medicine Compound Library

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Keywords

(-)-Oxypeucedanin hydrate 133164-11-1 Others cytotoxic ( ) Oxypeucedanin hydrate cell tumor inhibit Inhibitor ()Oxypeucedanin hydrate antiproliferative cancer OXYPEUCEDANIN HYDRATE Oxypeucedanin Hydrate inhibitor

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