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WAY-326766

Name: WAY-326766
Brand: TargetMol
SKU: T77604
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77604Cas No. 853138-67-7

WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).

WAY-326766

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Purity: 99.87%

Catalog No. T77604Cas No. 853138-67-7

WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	-	In Stock
5 mg	$74	-	In Stock
10 mg	$123	-	In Stock
25 mg	$247	-	In Stock
50 mg	$352	-	In Stock
100 mg	$487	-	In Stock
200 mg	$657	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.87%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

WAY-326766 AI Summary

WAY-326766 demonstrates bioactivities related to the inhibition and activation of Human alpha-Glucosidase, indicating its potential as a chaperone treatment for Pompe Disease. Additionally, it exhibits inhibitory effects on Polymerase Iota and Hepatitis C Virus (HCV)..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).

Chemical Properties

Molecular Weight	397.42
Formula	C₂₁H₂₃N₃O₅
Cas No.	853138-67-7
Smiles	C(C(NC=1C=C2C(=CC1)OCCO2)=O)(N(C(CNC(C)=O)=O)C)C3=CC=CC=C3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (125.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5162 mL	12.5811 mL	25.1623 mL	125.8115 mL
5 mM	0.5032 mL	2.5162 mL	5.0325 mL	25.1623 mL
10 mM	0.2516 mL	1.2581 mL	2.5162 mL	12.5811 mL
20 mM	0.1258 mL	0.6291 mL	1.2581 mL	6.2906 mL
50 mM	0.0503 mL	0.2516 mL	0.5032 mL	2.5162 mL
100 mM	0.0252 mL	0.1258 mL	0.2516 mL	1.2581 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc