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sAJM589

Catalog No. T16839 CAS 2089-82-9

sAJM589 is a Myc inhibitor(IC50: 1.8 μM).

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sAJM589, CAS 2089-82-9

Pack Size	Availability	Price/USD	Quantity
2 mg	5 days	$ 82.00
1 mL * 10 mM (in DMSO)	5 days	$ 112.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
Targets&IC50	MYC:1.8 μM
In vitro	sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose-dependent manner (IC50: 1.8 μM). sAJM589 inhibits cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage-independent growth of Raji cells [1].

Molecular Weight	246.26
Formula	C16H10N2O
CAS No.	2089-82-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5 mg/mL (20.30 mM), Sonification is recommended.

References and Literature

1. Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.

Related Products

Related compounds with same targets

Moracin T Moracin D c-Myc inhibitor 12 VPC-70063 10058-F4 c-Myc inhibitor 11 APTO-253 Nicotinamide N-oxide

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

sAJM589 2089-82-9 Cell Cycle/Checkpoint c-Myc sAJM 589 sAJM-589 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.