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RPA 202248

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Catalog No. T219132 Copy Product Info
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RPA 202248 is an inhibitor of para-hydroxyphenylpyruvate dioxygenase (HPPD) and a degradation product of isoxaflutole. It demonstrates environmental persistence and can migrate through soil matrices and macropores to reach subsurface drainage systems in agricultural environments.
RPA 202248
Cas No. 143701-75-1
Pack SizePriceUSA StockGlobal StockQuantity
10 mgInquiry10-14 weeks10-14 weeks
50 mgInquiry10-14 weeks10-14 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
RPA 202248 is an inhibitor of para-hydroxyphenylpyruvate dioxygenase (HPPD) and a degradation product of isoxaflutole. It demonstrates environmental persistence and can migrate through soil matrices and macropores to reach subsurface drainage systems in agricultural environments.
In vitro
RPA 202248 is a highly persistent chemical compound with significant water solubility, exhibiting an average aerobic soil half-life of 27.0 days and an average soil Koc of 139 cm³/g. Additionally, it remains stable against hydrolysis and aquatic photolysis at pH 7.
Chemical Properties
Molecular Weight359.32
FormulaC15H12F3NO4S
Cas No.143701-75-1
SmilesN#CC(C(=O)C1=CC=C(C=C1S(=O)(=O)C)C(F)(F)F)C(=O)C2CC2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
µL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: RPA 202248 chemical structure | RPA 202248 in vitro | RPA 202248 formula | RPA 202248 molecular weight