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Pinoresinol 4-O-β-D-glucopyranoside

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Catalog No. T4S0792Cas No. 69251-96-3
Alias (+)-pinoresinol-β-D-glucoside; (+)-pinor, (+)-pinoresinol-β-D-glucoside, (+)-pinor

(+)-pinoresinol-β-D-glucoside; (+)-pinor is the major active furanoid lignan in Lianxian. It shows antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory activities.

Pinoresinol 4-O-β-D-glucopyranoside

Pinoresinol 4-O-β-D-glucopyranoside

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Purity: 99.65%
Catalog No. T4S0792Alias (+)-pinoresinol-β-D-glucoside; (+)-pinor, (+)-pinoresinol-β-D-glucoside, (+)-pinorCas No. 69251-96-3
(+)-pinoresinol-β-D-glucoside; (+)-pinor is the major active furanoid lignan in Lianxian. It shows antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$103In StockIn Stock
10 mg$173In StockIn Stock
25 mg$293In StockIn Stock
50 mg$412In StockIn Stock
100 mg$581-In Stock
200 mg$785-In Stock
1 mL x 10 mM (in DMSO)$136In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.65%
Color:White
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Product Introduction

Pinoresinol 4-O-β-D-glucopyranoside AI Summary
Pinoresinol 4-O-β-D-glucopyranoside exhibits notable antiestrogenic activity in both human MCF7 and T47D cell lines. In MCF7 cells, it effectively inhibits cell proliferation enhanced by 100 pM E2 to levels equivalent to 50, 10, and 1 pM E2, with an activity of less than 0.1 µM. In T47D cells, the compound reduces cell proliferation to levels equivalent to 50 and 10 pM E2 at concentrations of less than 0.1 µM, though at 1 pM E2, the activity is significantly less potent, exceeding 100.0 µM. Furthermore, at concentrations ranging from 0.1 to 100 µM, Pinoresinol 4-O-β-D-glucopyranoside inhibits E2-enhanced cell proliferation by more than 90% in T47D cells. In addition to its antiestrogenic properties, Pinoresinol 4-O-β-D-glucopyranoside demonstrates antioxidant activity. It scavenges superoxide radicals with an EC50 of 18,550.0 nM, although its DPPH radical scavenging activity is markedly weaker, with an EC50 greater than 100,000.0 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
(+)-pinoresinol-β-D-glucoside; (+)-pinor is the major active furanoid lignan in Lianxian. It shows antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory activities.
Synonyms(+)-pinoresinol-β-D-glucoside; (+)-pinor, (+)-pinoresinol-β-D-glucoside, (+)-pinor
Chemical Properties
Molecular Weight520.53
FormulaC26H32O11
Cas No.69251-96-3
Smiles[H][C@]12CO[C@H](c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)[C@@]1([H])CO[C@@H]2c1ccc(O)c(OC)c1
Relative Density.1.418 g/cm3 (Predicted)
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (86.45 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.84 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9211 mL9.6056 mL19.2112 mL96.0559 mL
5 mM0.3842 mL1.9211 mL3.8422 mL19.2112 mL
10 mM0.1921 mL0.9606 mL1.9211 mL9.6056 mL
20 mM0.0961 mL0.4803 mL0.9606 mL4.8028 mL
50 mM0.0384 mL0.1921 mL0.3842 mL1.9211 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

pinoresinol-β-D-glucoside; pinorpinoresinol-β-D-glucosidepinoresinol-beta-D-glucoside; pinorpinoresinol-beta-D-glucosidepinoresinol-b-D-glucoside; pinorpinoresinol-b-D-glucosidePinoresinol 4-O-β-D-glucopyranosidePinoresinol 4OβDglucopyranosidePinoresinol 4-O-beta-D-glucopyranosidePinoresinol 4-O-b-D-glucopyranosidePinoresinol 4 O β D glucopyranosidepinorphosphodiesteraselignansInhibitorinhibitfurofuran typecAMPantioxidant
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