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nor-NOHA acetate

Catalog No. T12240   CAS 1140844-63-8
Synonyms: Nω-Hydroxy-nor-L-arginine acetate

nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) is a reversible inhibitor of arginase, with anti-leukemic activity, effective in endothelial dysfunction, immunosuppression, and metabolism.

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nor-NOHA acetate Chemical Structure
nor-NOHA acetate, CAS 1140844-63-8
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Biological Description
Chemical Properties
Storage & Solubility Information
Description nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) is a reversible inhibitor of arginase, with anti-leukemic activity, effective in endothelial dysfunction, immunosuppression, and metabolism.
Synonyms Nω-Hydroxy-nor-L-arginine acetate
Molecular Weight 296.28
Formula C9H20N4O7
CAS No. 1140844-63-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 200 mg/mL (675.04 mM), sonification is recommended.

TargetMolReferences and Literature

1. Ng KP, et al. The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLoS One. 2018 Oct 11;13(10):e0205254.

Related compound libraries

This product is contained In the following compound libraries:
Apoptosis Compound Library NO PAINS Compound Library

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Keywords

nor-NOHA acetate 1140844-63-8 Apoptosis Immunology/Inflammation Arginase nor-NOHA Nomega-Hydroxy-nor-L-arginine Acetate inhibit nor-NOHA Acetate nor NOHA acetate Nω-Hydroxy-nor-L-arginine acetate Nw-Hydroxy-nor-L-arginine Acetate Nω-Hydroxy-nor-L-arginine Acetate norNOHA acetate Inhibitor inhibitor

 

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