UBE2K Protein, Human, Recombinant (GST)

Catalog No. TMPJ-01038 Copy Product Info

UBE2K Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45 KDa and the accession number is P61086.

UBE2K Protein, Human, Recombinant (GST)

Catalog No. TMPJ-01038

Copy Product Info

UBE2K Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45 KDa and the accession number is P61086.

Pack Size	Price	USA Stock	Global Stock
10 μg	$35	2-4 weeks	2-4 weeks
20 μg	$51	2-4 weeks	2-4 weeks
50 μg	$91	2-4 weeks	2-4 weeks
100 μg	$168	2-4 weeks	2-4 weeks
200 μg	$325	2-4 weeks	2-4 weeks
500 μg	$781	2-4 weeks	2-4 weeks
1 mg	$1,120	2-4 weeks	2-4 weeks

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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	UBE2K Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45 KDa and the accession number is P61086.
Species	Human
Expression System	E. coli
Tag	N-GST
Accession Number	P61086
Synonyms	Ubiquitin-Protein Ligase,Ubiquitin-Conjugating Enzyme E2-25K,Ubiquitin-Conjugating Enzyme E2-25 kDa,Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin-Conjugating Enzyme E2 K,Ubiquitin Carrier Protein,UBE2K,Huntingtin-Interacting Protein 2,HIP-2,HIP2
Amino Acid	Met1-Asn200
Construction	Met1-Asn200
Molecular Weight	45 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.