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hDHODH-IN-7

Catalog No. T11031   CAS 1644156-41-1
Synonyms: DHODH-IN-9

hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.

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hDHODH-IN-7 Chemical Structure
hDHODH-IN-7, CAS 1644156-41-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 195.00
2 mg In stock $ 293.00
5 mg In stock $ 449.00
10 mg In stock $ 659.00
25 mg In stock $ 987.00
50 mg In stock $ 1,390.00
100 mg In stock $ 1,880.00
500 mg In stock $ 3,780.00
1 mL * 10 mM (in DMSO) In stock $ 468.00
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Purity: 99.82%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.
Targets&IC50 DHODH:pMIC50:7.4
In vitro hDHODH-IN-7 is the corresponding pyridazine homologue from 3-chloro-6-cyclopropylpyridazine. There is almost no change, and the antiviral mode of action of the analogs with 5-cyclopyridine reflects the antiviral effect of homologues with 5-ethylpyrimidinyl groups to some extent. hDHODH-IN-7 is a good antiviral agent for such analogs[1].
Synonyms DHODH-IN-9
Molecular Weight 366.43
Formula C21H23FN4O
CAS No. 1644156-41-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (136.45 mM)

TargetMolReferences and Literature

1. Lucas-Hourani M, et al.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98.

Related compound libraries

This product is contained In the following compound libraries:
Inhibitor Library Anti-Cancer Metabolism Compound Library Mitochondria-Targeted Compound Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Viral Compound Library

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11β-HSD1-IN-12 Succinyl phosphonate trisodium salt LDCA Methotrexate disodium 4-Hydroxyderricin Ammonium Glycyrrhizinate Devimistat TC HSD 21

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Keywords

hDHODH-IN-7 1644156-41-1 Metabolism Dehydrogenase hDHODH IN 7 DHODH-IN-9 hDHODHIN7 inhibitor inhibit

 

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