Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 157.00 | |
5 mg | In stock | $ 390.00 | |
10 mg | Inquiry | $ 578.00 | |
25 mg | Inquiry | $ 928.00 | |
50 mg | Inquiry | $ 1,260.00 |
Description | GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases. |
In vivo |
GSK2292767 in a brown Norwegian rat acute OVA model of Th2 driven pulmonary inflammation in rats 35 μg/kg of ED50 protects eosinophil recruitment.[1] In rat PK studies, GSK2292767 showed a high clearance rate (50 mL/min/kg) and low oral bioavailability (F<2%) in vivo.[1] |
Synonyms | GSK2292767 FA(1254036-66-2 Free base) |
Molecular Weight | 558.61 |
Formula | C25H30N6O7S |
CAS No. | T6850L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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GSK2292767 FA T6850L PI3K/Akt/mTOR signaling PI3K GSK2292767 FA(1254036-66-2 Free base) inhibitor inhibit