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Flusulfinam

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Catalog No. T218330 Copy Product Info
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Flusulfinam is an HPPD inhibitor and herbicide (Herbicide) with an IC50 of 0.0181 μM for Arabidopsis thaliana HPPD. It inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD and demonstrates strong herbicidal activity against barnyard grass (Echinochloa crus-galli). Additionally, Flusulfinam suppresses the growth of crabgrass (Digitaria sanguinalis).

Flusulfinam

Cas No. 2428458-82-4
Pack SizePriceUSA StockGlobal StockQuantity
10 mgInquiry10-14 weeks10-14 weeks
50 mgInquiry10-14 weeks10-14 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Flusulfinam is an HPPD inhibitor and herbicide (Herbicide) with an IC50 of 0.0181 μM for Arabidopsis thaliana HPPD. It inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD and demonstrates strong herbicidal activity against barnyard grass (Echinochloa crus-galli). Additionally, Flusulfinam suppresses the growth of crabgrass (Digitaria sanguinalis).
In vitro
Flusulfinam (0.94-30 g a.i. ha-1) exhibits potent herbicidal activity against Echinochloa crus-galli, causing leaf chlorosis and plant death, with a GR50 of 3.7235 ± 0.7995 g a.i. ha-1. At a concentration of 25 mg/L, Flusulfinam reduces chlorophyll content in Spirodela polyrhiza. The compound strongly inhibits the catalytic activity of recombinant Arabidopsis HPPD in vitro, with an IC50 of 0.0181 ± 0.0021 μM, showing 16 times the potency of Mesotrione. When applied as a foliar spray, Flusulfinam inhibits the growth of Digitaria sanguinalis, with an EC50 of 21.91 mg/L.
In vivo
Flusulfinam exhibits acute toxicity to juvenile zebrafish (Danio rerio) with an LC50 of 62.61 mg/L when exposed for 96 hours.
Chemical Properties
Molecular Weight379.33
FormulaC14H13F4N3O3S
Cas No.2428458-82-4
SmilesO=C(NC1=NN=C(O1)C)C2=CC=C(C(=C2F)S(=O)CCC)C(F)(F)F
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Flusulfinam in vivo | Flusulfinam in vitro | Flusulfinam formula | Flusulfinam molecular weight