Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor. |
In vivo | In dialysate dopamine concentrations significantly increased by Vinconate (50 to 200 mg/kg p.o.). Daily treatment with Vinconate (25 mg/kg) for 7 days also significantly increases dopamine and serotonin concentrations in dialysate[1]. In [3H]QNB binding in the nucleus accumbens and cerebellum, Chronic treatment with Vinconate at a 10 mg/kg significantly ameliorats the reduction . Furthermore, this Vinconate treatment significantly enhances [3H]QNB binding in the frontal cortex and hippocampus compare with the vehicle-treated aged animals. Also, chronic treatment with Vinconate at the higher dose significantly elevates [3H]QNB binding in the hippocampal CA3 sector and dentate gyrus compare with the vehicle-treated aged animals. Chronic treatment with Vinconate at a dose of 10 mg/kg shows a significant reduction in [3H]HC binding only in the hippocampal CA1 sector compare with the vehicle-treated aged rats[2]. |
Synonyms | Chanodesethylapovincamine |
Molecular Weight | 296.36 |
Formula | C18H20N2O2 |
CAS No. | 70704-03-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Vinconate 70704-03-9 Others Chanodesethylapovincamine Chanodesethylapovincamine inhibitor inhibit