Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 39.00 | |
100 mg | In stock | $ 57.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects. |
In vivo | Sodium gualenate has been frequently used for the treatment of human gastritis. Cytoprotection is defined as the main mechanism of Sodium gualenate to protect the mucosa of the stomach[1]. |
Animal Research | The anti-gastric ulcer activity of compounds was tested through an ethanol-induced gastric ulcer mouse model method.?Kunming mice, consisting of both males and females, each weighing about 25 g, were divided into groups of 8 at random.?The tested compounds, Omeprazole and guaiazulene derivatives which were made into suspensions using 5% CMC-Na were administered orally (0.4 mL/20 g) to the dose group, the drug reference group and the GAS-Na group respectively.?While the base control group was treated with only 5% CMC-Na.?Vehicle or test compounds were administered by the oral route once a day for five consecutive days.?After 0.5 h of the last dose, the mice were given orally 0.3 mL of anhydrous ethanol.?Half an hour after anhydrous ethanol administration, the animals were killed.?At last, the stomachs were removed and scored[1]. |
Synonyms | Guaiazulenesulfonate sodium |
Molecular Weight | 300.35 |
Formula | C15H17NaO3S |
CAS No. | 6223-35-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (99.88 mM)
You can also refer to dose conversion for different animals. More
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Sodium gualenate 6223-35-4 Others Inhibitor inhibit Guaiazulenesulfonate Guaiazulenesulfonate sodium inhibitor