Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Saprorthoquinone is a natural product from Salvia prionitis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 1,090.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 1,110.00 |
Description | Saprorthoquinone is a natural product from Salvia prionitis. |
In vitro | Ten diterpenoids [6a-hydroxysalvinolone (1 ), 6a-hydroxytaxodone (2 ), aethiopinone (3 ), microstegiol (4 ), ferruginol (5 ), Saprorthoquinone (6 ), 11,12-dioxoabieta-8,13-diene (7 ), taxodione (8 ), hypargenin A (9 ), hypargenin D (10 )] and three triterpenoids [lupeol 3-acetate, d-oleanol 3-acetate and -sitosterol] were isolated from the roots of Salvia hypargeia , a plant endemic to Turkey. METHODS AND RESULTS: The crude extract and compounds 1-2 , 5-10 were tested against a panel of human cancer cell lines [human breast cancer (BC 1), human lung cancer (LU 2), human colon cancer (COL 2), human epidermoidal carcinoma in mouth (KB), vinblastine-resistant KB-VI, hormone-dependent human prostate cancer (LNCaP)] as well as P388 and ASK cells in culture. CONCLUSIONS: The crude extract was active in all of the test systems, except KB. Isolates 1 and 8 were also found to mediate a generalized cytotoxic response. |
Source |
Molecular Weight | 296.4 |
Formula | C20H24O2 |
CAS No. | 102607-41-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Saprorthoquinone 102607-41-0 inhibitor inhibit