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Quercetin 3-gentiobioside

Catalog No. TN2122 CAS 7431-83-6

Synonyms: Quercetin-3-gentiobioside

Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).

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Quercetin 3-gentiobioside Chemical Structure

Quercetin 3-gentiobioside, CAS 7431-83-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 109.00
5 mg	In stock	$ 276.00
10 mg	In stock	$ 469.00
25 mg	In stock	$ 759.00
50 mg	In stock	$ 987.00
1 mL * 10 mM (in DMSO)	In stock	$ 393.00

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Purity: 99.77%

Purity: 99.29%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).
Targets&IC50	AGE:109.46±1.41, AR:10.6±0.38
In vitro	We led to isolation of Quercetin-3-gentiobioside was first reported on the isolation from A. iwayomogi. A. iwayomogi extracts showed significant inhibitor on AR and AGEs formation activities[1] We also determined quercetin 3-O-gentiobioside have antioxidant activity in vitro.[2]
In vivo	Treatment with quercetin 3-O-gentiobioside (HF diet-induced obese mice; 0.1% Iso and Que) reduced blood glucose and serum insulin levels and improved glucose tolerance in obese mice. Meanwhile, serum triglyceride levels and liver morphology in the mice were significantly ameliorated by EO and isoquercitrin treatment. Total cholesterol levels in quercetin 3-O-gentiobioside treated mice were also reduced.[2]

Synonyms	Quercetin-3-gentiobioside
Molecular Weight	626.52
Formula	C27H30O17
CAS No.	7431-83-6

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90.0 mg/mL (143.6 mM), Sonication is recommended.

References and Literature

1. Lee YK, et al. Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds. Biomed Res Int. 2017;2017:7375615. 2. Fan S, et al. Extract of okra lowers blood glucose and serum lipids in high-fat diet-induced obese C57BL/6 mice. J Nutr Biochem. 2014;25(7):702-709.

Related compound libraries

This product is contained In the following compound libraries：

Miao medicine Compound Library Inhibitor Library Flavonoid Natural Product Library Polyphenolic Natural Product Library Bioactive Compounds Library Max Natural Product Library for HTS Selected Plant-Sourced Compound Library Bioactive Compound Library Traditional Chinese Medicine Monomer Library

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Keywords

Quercetin 3-gentiobioside 7431-83-6 Endocrinology/Hormones Metabolism Reductase Quercetin-3-gentiobioside inhibitor inhibit

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