Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | Inquiry | |
1 mL * 10 mM (in DMSO) | In stock | $ 82.00 |
Description | PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36). |
Targets&IC50 | Ghrelin receptor:8.36 (pKi) |
In vitro | PF-5190457 has a superior balance of ghrelin receptor pharmacology. It also has off-target selectivity [1]. |
In vivo | In human whole and dispersed islets, PF-5190457 has excellent selectivity and demonstrates robust increases in glucose-stimulated insulin secretion[1]. |
Synonyms | PF-05190457 |
Molecular Weight | 512.67 |
Formula | C29H32N6OS |
CAS No. | 1334782-79-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (487.64 mM), Sonification is recommended.
Ethanol: 100 mg/mL (195.06 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PF-5190457 1334782-79-4 GPCR/G Protein GHSR Growth hormone secretagogue receptor PF05190457 PF 5190457 PF-05190457 Inhibitor PF5190457 inhibit PF 05190457 inhibitor