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NVP-QAV-572

Name: NVP-QAV-572
Brand: TargetMol
SKU: T12275
Rating: 4.5 (1 reviews)

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Catalog No. T12275Cas No. 957209-68-6

NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).

NVP-QAV-572

😃Good

Catalog No. T12275Cas No. 957209-68-6

NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$247	8-10 weeks	8-10 weeks
25 mg	$766	8-10 weeks	8-10 weeks
50 mg	$996	8-10 weeks	8-10 weeks
100 mg	$1,490	8-10 weeks	8-10 weeks
1 mL x 10 mM (in DMSO)	$279	8-10 weeks	8-10 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).
Targets&IC50	PI3K:10 nM
In vitro	NVP-QAV-572 is useful in the treatment of conditions which are mediated by the activation of the Pi3 kinase enzymes, used in inflammatory or allergic conditions[1].

Chemical Properties

Molecular Weight	471.5
Formula	C₁₇H₁₉F₂N₇O₃S₂
Cas No.	957209-68-6
Relative Density.	1.59±0.1 g/cm3 (20 °C, 760 mmHg)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (265.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1209 mL	10.6045 mL	21.2089 mL	106.0445 mL
5 mM	0.4242 mL	2.1209 mL	4.2418 mL	21.2089 mL
10 mM	0.2121 mL	1.0604 mL	2.1209 mL	10.6045 mL
20 mM	0.1060 mL	0.5302 mL	1.0604 mL	5.3022 mL
50 mM	0.0424 mL	0.2121 mL	0.4242 mL	2.1209 mL
100 mM	0.0212 mL	0.1060 mL	0.2121 mL	1.0604 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc