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MP7

Catalog No. T12398 CAS 1001409-50-2

Synonyms: PDK1 inhibitor

MP7 (PDK1 inhibitor) is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

MP7, CAS 1001409-50-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 45.00
5 mg	In stock	$ 110.00
10 mg	In stock	Inquiry
50 mg	In stock	Inquiry
1 mL * 10 mM (in DMSO)	In stock	$ 125.00

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Purity: 99.66%

ee: 100%

Purity: 99.45%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	MP7 (PDK1 inhibitor) is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).
In vitro	MP7 are able to decrease the number of viable cells. When combined together, GSC viability is further reduced with respect to single-treated cells. As observed in U87MG cells, when used at the highest concentrations (i.e., 1.5 μM Alisertib and 2.5 μM MP7), a significant enhancement in the number of dead cells is evidenced. Following 72 h treatment.

Synonyms	PDK1 inhibitor
Molecular Weight	516.5
Formula	C28H22F2N4O4
CAS No.	1001409-50-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: ≥ 100 mg/mL (193.61 mM)

H2O: < 0.1 mg/mL (insoluble)

References and Literature

1. Daniele S, et al. Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells. ACS Chem Neurosci. 2017 Jan 18;8(1):100-114.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Obesity Compound Library Kinase Inhibitor Library Anti-Prostate Cancer Compound Library Glycolysis Compound Library Neuronal Differentiation Compound Library Anti-Colorectal Cancer Compound Library Bioactive Compound Library Anti-Pancreatic Cancer Compound Library Antioxidant Compound Library

Related Products

Related compounds with same targets

Osu03012 JX06 PS10 PDK1-IN-RS2 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile PDK4-IN-1 hydrochloride PHT-427 PS 48

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MP7 1001409-50-2 PI3K/Akt/mTOR signaling PDK PDK1 inhibit Inhibitor kinase-1 PDK-1 PDK1 inhibitor phosphoinositide-dependent MP-7 MP 7 inhibitor

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