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Herpetone

Catalog No. TN1732 CAS 951677-22-8

Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (<a href="/target/HBV" style="display: inline; color: #c13a36">HBV</a>) activity.

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Herpetone, CAS 951677-22-8

Pack Size	Availability	Price/USD	Quantity
5 mg	Inquiry	$ 320.00
1 mL * 10 mM (in DMSO)	Inquiry	$ 490.00

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Purity: 98%

Biological Description

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Description

Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.

In vitro

Herpetin (HPT), Herpetone (HPO), and herpetfluorenone (HPF) were isolated from HS and identified using HR-ESI-MS and NMR. Different concentrations of the drugs were added to the HepG2.2.15 cells. Cell toxicity was observed with an MTT assay, cell culture supernatants were collected, and HBsAg and HBeAg were detected by ELISA. The content of HBV DNA was determined via quantitative polymerase chain reaction (PCR) with fluorescent probes. The 50% toxicity concentration (TC50) of HPF was 531.48 μg/mL, suggesting that this species is less toxic than HPT and HPO.

Molecular Weight	522.55
Formula	C29H30O9
CAS No.	951677-22-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Anti-HBV Activities of Three Compounds Extracted and Purified from Herpetospermum Seeds.Molecules. 2016 Dec 27;22(1). pii: E14.

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Keywords

Herpetone 951677-22-8 Microbiology/Virology HBV Inhibitor inhibitor inhibit

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