Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bitertanol (KWG 0599) is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 70.00 | |
25 mg | In stock | $ 114.00 | |
50 mg | In stock | $ 167.00 | |
100 mg | In stock | $ 248.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 63.00 |
Description | Bitertanol (KWG 0599) is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis. |
In vivo | Bitertanol (10, 25, and 100 mg/kg) produced 2-, 4-, and 14-fold increases of 7-ethoxyresorufin O-deethylation activity in liver microsomes, respectively. Bitertanol (25 mg/kg) increased CYP1A1 protein in the liver, kidney, and lung by 10-, 13-, and 17-fold, respectively. Bitertanol produced smaller increases of CYP2B and CYP3A catalytic activity and protein than that of CYP1A1 in liver. Additions of 0.01-100 microM Bitertanol to liver microsomes from rats Bitertanol (25 mg/kg) inhibited microsomal 7-ethoxyresorufin O-demethylation activity (IC50=0.8 microM). Bitertanol (100 mg/kg) increased liver UDP-glucuronosyltransferase and glutathione S-transferase activities by 2-fold. Bitertanol (25 mg/kg) produced a minor increase in metabolic activation of benzo[a]pyrene by liver S-9 fraction in the Ames mutagenicity test while the increase was blocked by addition of 100 microM Bitertanol[2]. |
Synonyms | KWG-0599, KWG0599, Baycor, Biloxazol, KWG 0599, Sibutol |
Molecular Weight | 337.42 |
Formula | C20H23N3O2 |
CAS No. | 55179-31-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (35.56 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Bitertanol 55179-31-2 Microbiology/Virology Antifungal KWG-0599 KWG0599 Baycor Biloxazol KWG 0599 Sibutol inhibitor inhibit