Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Auxinole, a potent antagonist of TIR1/AFB auxin receptors, effectively binds to TIR1, inhibiting the formation of the TIR1-IAA-Aux/IAA complex. This action blocks auxin-responsive gene expression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 75.00 | |
10 mg | In stock | $ 108.00 | |
25 mg | In stock | $ 179.00 | |
50 mg | In stock | $ 265.00 | |
100 mg | In stock | $ 397.00 | |
500 mg | In stock | $ 945.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 86.00 |
Description | Auxinole, a potent antagonist of TIR1/AFB auxin receptors, effectively binds to TIR1, inhibiting the formation of the TIR1-IAA-Aux/IAA complex. This action blocks auxin-responsive gene expression. |
In vitro | Auxinole is a potent auxin antagonist of TIR1/AFB receptors. It also binds TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and then inhibits auxin-responsive gene expression. Auxinole causes reduction in IAA-triggered depolarization in root hair cells. In addition, Auxinole competitively inhibits various auxin responses in planta[1]. Auxinole (20?μM) also represses the transient increase in [Ca2+]cyt completely, and blocks Ca2+ response[2]. |
Molecular Weight | 321.37 |
Formula | C20H19NO3 |
CAS No. | 86445-22-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 12.5 mg/mL (38.90 mM), Sonication is recommended.
DMSO: 125 mg/mL (388.96 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Auxinole 86445-22-9 Others Inhibitor inhibit inhibitor