Shopping Cart

Remove All
Your shopping cart is currently empty

Proceed to checkout Continue shopping

Asp-AMS

Name: Asp-AMS
Brand: TargetMol
SKU: T10386
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T10386Cas No. 828288-98-8

Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.

Asp-AMS

😃Good

Catalog No. T10386Cas No. 828288-98-8

Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.

Pack Size	Price	Availability
25 mg	$1,400	6-8 weeks
50 mg	$1,820	6-8 weeks
100 mg	$2,500	6-8 weeks

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Resource Download

Product Introduction

Bioactivity

Description

Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.

In vitro

Asp-AMS is a 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM) and a 35-fold weaker competitor of human and bovine cyt-AspRSs (300 nM). It exhibits the highest inhibitory effect on the mitochondrial enzyme and is the most active inhibitor with Ki values in the nanomolar range, having a stronger effect on bacterial AspRSs (E. coli and P. aeruginosa) than on human cytosolic AspRS.

Chemical Properties

Molecular Weight	461.41
Formula	C₁₄H₁₉N₇O₉S
Cas No.	828288-98-8
Relative Density.	2.14 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (216.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1673 mL	10.8363 mL	21.6727 mL	108.3635 mL
5 mM	0.4335 mL	2.1673 mL	4.3345 mL	21.6727 mL
10 mM	0.2167 mL	1.0836 mL	2.1673 mL	10.8363 mL
20 mM	0.1084 mL	0.5418 mL	1.0836 mL	5.4182 mL
50 mM	0.0433 mL	0.2167 mL	0.4335 mL	2.1673 mL
100 mM	0.0217 mL	0.1084 mL	0.2167 mL	1.0836 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc