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Argipressin

Catalog No. T7434 CAS 113-79-1

Synonyms: Arg8-vasopressin, AVP, Vasopressin

Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine <a href="/target/Vasopressin_Receptor" style="display: inline; color: #c13a36">Vasopressin Receptor</a>, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.

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Argipressin, CAS 113-79-1

Pack Size	Availability	Price/USD
1 mg	In Stock (ship within 1 week)	$ 46.00
2 mg	In Stock (ship within 1 week)	$ 58.00
5 mg	In Stock (ship within 1 week)	$ 91.00
10 mg	In Stock (ship within 1 week)	$ 120.00
25 mg	In Stock (ship within 1 week)	$ 159.00
50 mg	In Stock (ship within 1 week)	$ 189.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.
In vitro	Argipressin stimulates the intracellular release of calcium in A7r5 cells (EC50 = 5 nM)[1].
In vivo	In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.

Synonyms	Arg8-vasopressin, AVP, Vasopressin
Molecular Weight	1144.29
Formula	C48H69N15O14S2
CAS No.	113-79-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 100 mg/mL (92.23 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Byron K L . Vasopressin Stimulates Ca2+ Spiking Activity in A7r5 Vascular Smooth Muscle Cells via Activation of Phospholipase A2[J]. Circulation Research, 1996, 78(5):813-20. 2. Jiang N C , Gao L , Chen C , et al. Effects of argipressin injected into medial amygdaloid body on blood pressure and heart rate in rats[J]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, 14(2):118-120.

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Keywords

Argipressin 113-79-1 GPCR/G Protein Vasopressin Receptor Arg8-vasopressin Inhibitor inhibit AVP Vasopressin inhibitor

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